1. Hakuoro luv Mikoto, Mikoto is cloned from him. Close to a cousin or a half sister.
2. Mutsumi luv Hakuoro (sexually), Hakuoro thinks of her as a daughter. Same relationship as Mikoto.
3. Eruru is the great, great, great, great, great, great, great grand daughter of Hakuoro and Mikoto on her father's side. Aruru is the same.
Everyone else is related to him but even less distantly than Eruru/Aruru. His closest living relative when he woke up was Tuskuru.
tl;dr - Hakuoro is ADAM, Mikoto is EVE. Would you call Adam fucking say Aya Hirano incest?