ITT: Game Settings that should be Anime

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Deadlands: The Weird West.

The Wild West with monsters and undead wreaking havok.

In 1865 this Indian Shaman decides to throw open the gates of hell and allow evil spirits called Manitous (demons to the white man) to wreak revenge upon the white man. Turning the dead into zombies and creating all manner of horrible beasts and monsters upon the countryside. The Civil War is drawn out for 13 years because every time they fight all manner of monsters are created.