OP here. Thanks /a/non.
I've seen some of Maison Ikkoku, and read some of the manga, but unfortunately not all of either. Now that you've reminded me, I'll look into getting the rest.
As for Love Hina, I guess it was college level... sort of... but it's such a harem focused show it doesn't really match the genre I was picturing.
Ah My Goddess would be another series in that category. Keiichi is in college for most of the series, but the whole living-with-goddesses thing tends to overshadow that aspect.
Paradise kiss might be worth looking into, although I seem to recall seeing the first episode and being unimpressed. The 'only fashion school' thing isn't that big a deal, considering all but one of the series in my original list were set in somewhat specialized colleges (art, music, agriculture).
Also, it occurs to me that NHK ni Youkoso sort of qualifies as well, even if it's 'only game design school', and the main character isn't the one attending.