Madara got his ass beat by The First even with Eternal Mangekyou.
Pointless power up is pointless in the grand scheme of things. He'll most likely fail about half way through, get his ass beat, and then get a long winded lecture/rant from Naruto after Naruto beat the shit out of him.
Madara is more likely to do some damage.
Also, Tsunade was confirmed dead the moment Jiraiya died.