When Caska was a child, Griffith saved her from being raped by a nobleman.
Caska was created among Griffith and his troops, and eventually fell in love with Guts, who left her just before Griffith got arrested. So, she lost two of the most important people to her.
Shortly after she helped saving Griffith, Caska & co. where sent to a fucking hell with demons and she was raped by the man who she admired so fucking much. Isn't that fucking disturbing?
Guts also suffered, but he had much weaker emotional bonds to the people who got killed there.