Sanctuary is awesome manga about two guys trying to change old and shitty Japan. One of them is politician, the other one - yakuza. Not deep, has great charactres, some good humor, and pretty intresting story. Picture related.
Eden is probably the best cyberpunk manga, that you can find. Great story that develops on multiple levels (global stuff, main character personal problems, local mafia wars). Art is pretty simplistic, but good, good fighting scenes.
Parasite has pretty shitty art, but that's the only problem. Main character stuck with the alien life form that failed to capture his body, and now they are trying to survive. Has some nice humor and horror elements.