Gundam 08th MS Team: Will always be in my top 3. It was the first love story I was old enough to appreciate as a love story, but more than that it may be the best Gundam ever made.
Gurren Lagann: There may be debate about this anime every damn day, but I think its amazing, and I'll want to have it around so I can "oh shit!" at those epic moments all over again.
Azumanga: Will always be funny. I laugh my brains out all over again every time I watch this show, and BAW at the last episode every damn time.
Evangelion: The first anime DVD's I ever bought, I will take these to the grave. I love this show, and no one will ever be able to tell me its not awesome. Its like Transformers to me, unimpeachable in my own view of its awesomeness. Also, I liked End of Eva. There, I said it.
Negima (manga): I will not rest until I have every single book of this series on perfect display. I love it. Its the best manga I've ever read. Period.
Rozen Maiden: Its funny, its artsy, its dramatic, its got loveable and well designed characters. The story isn't even bad, and thats saying something considering its about barbie dolls having pokemon battles.
Princess Mononoke: Nothing needs to be said.