It's from an old short series called "Boku no Pico". The story revolves around Pico, a teenage male who goes to a highschool during his days, but does not actually go for lessons. He is only there because he loves his homeroom teacher's young daughter, pictured in OP.
The series revolves around Pico trying to get together with an underage girl. It's mostly comedy, but it has its sad points.