GutsxGriffith clearly have a homosexual relationship. Guts hates Griffith since he had sex with a woman in front of Guts, thus making him jealous and crying like a little girl. I believe that when they finally meet again, Guts will talk about his true feelings and they will make sweet little children.
Also, the relationship of Naruto and Sasuke is very deep and interesting, as is the rest of that stunning manga with unbelievable art. Silly shonen comedy crap like Berserk isn't worthy of comparison.