I just read the manga, but watched the anime episodes corresponding to the few volumes that are missing from the scanlations because I didn't want to skip anything.
Watching Ken and Rei kill random thugs gets a bit old after the first SEVERAL HUNDRED. Seriously, how big was that fucking Fang Clan? Then the rescue Toki arc was all "THANK YOU KEN! BUT YOUR JESUS IS IN ANOTHER CASTLE". It was quite the chore watching until something important finally happened. Then it was awesome, but in the manga you get the awesome faster.