even in a small studio not a big one there is a pipeline, or i suppose you could call it workflow?
for example somewhere i work is
Maya > Zbrush > 3Dcoat (UV / Retop).
then Quixle / Photoshop / Rarely Mari
then Nuke or if motion graphics AE.
steps can be skipped project depending. but if you look at the places you want to work, id always pick the two or three most popular applications and learn those. even if you get a job with great work in a program they don't use. its gonna suck learning multiple programs as you work in a new job.