Small studio where you are expected to make shit?
Or a position that looks for knowledge in a specific package?
Dont even bother.
But if you are good and are trying to get a job in a larger indie team or aaa then they wont give a shit if you model in wordpad by typing out vertex positions and save it as obj.
Actually just watched an panel by ID software, lead artists was talking how he dont care what you can do overall or what you work in, just as long as you are good at one thing and are ready to learn.
But i guess if you are asking they you wont really blow anybody away with your folio, so if you are starting its better to at lest know how to use max and maya if not to be proficient in the them.
Then you can just say you know they and hope for best later,